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This variability underscores the importance of understanding that weight loss is a complex process influenced by numerous factors, and no single treatment works the same for everyone

Lancet 343 , 45 (1994)

We recommend weekly injections the first month of your treatment, and then injections every 4 weeks to maintain benefits

The concomitant use of topiramate with other carbonic anhydrase inhibitors or in patients on a ketogenic diet may create a physiological environment that increases the risk of kidney stone formation and should therefore be avoided

Gross-total resection (GTR) was the treatment of choice in all amenable cases, followed in selected cases with residual tumor by adjuvant radiotherapy or chemotherapy